The ubiquitous computing technology has realized Andre Malraux’s ideal of “museums without walls” to a certain degree by increasing the accessibility in the digital world. The abundant mobile applications available now concerning multimedia guide, podcast publication, and education games serve as attractive communication channels to reach out for the visitors while offering alternative exhibition interpretations with interaction possibilities. However, to those medium-small size museums, the mobile application are often not applied due to limited resources in budget and personnel. Therefore, a distributed mobile guide application platform in being developed and on its way to meet the needs in Finland as well as in other Nordic countries. To bring this distributed mobile guide application in use to Asia, this paper is to take a Finnish art exhibition that will be hosted in Beijing China as a case study, to explore how to localize this application in terms of the user interface design, information architecture, social media strategy, and location aware service. The cross-cultural communication features of a museum mobile application, is then the core issue here to speak in general. Ideally, there is no border online and mobile, however except the linguistic challenge and the telecommunication infrastructure condition, the user experience also varies significantly from culture to culture. The development of museum history is to go democratic from the social cultural aspect of the institution to the involving participants targeted by museum exhibitions and education programs. The mobile application is in line with it and can be influential in many dimensions, especially in China. The goal of this application is to increase the impact of the exhibition, to generate societal discussion, and to enhance cultural exchange. Along with the implementation after the concept design, challenges will be identified in a concrete sense and be dealt with, technically and theoretically.